Well, I was wrong about the location. This was taken from behind, looking in to the HR, not from across the floor.
But listen to the lack of buzz. This was a mike with a parabolic dish being pointed at the doorkeeper because they wanted to pick up the “Mr. Speaker: His Holiness, Pope Francis!”
Which means whoever said it was either in very, very close proximity to the soundman or in a direct line between the sound man and the Pope, who you see standing there in the door. Which, in turn, pretty much has to mean it was a staffer or a reporter. And no, next to no chance it was just small talk. It was a nasty little crack about throwing a shoe at the Pope.