Thank you for your compelling personal story. You really know the scope of the disorder, from your milder, functional depression to your wife’s very serious disorder. I wish the best outcomes possible for both of you.
With compassion and hope. 
It’s important to talk about the hearing aids, and eyesight, and all of our senses. When our brain is slowly (or suddenly) deprived of the normal sensations of life, hearing birds singing, songs, speech, talking on the phone. Seeing the colors all around us and being able to read a newspaper or a novel, or a great text, Seeing a beautiful photo or painting. A movie or a play. The pleasure of a touch. The smell of baking bread, or a trout stream in the spring. OMG, even the smell of a cigarette outside on a bright spring day. When those senses fade, or are lost, it really changes the receptors and neurotransmitters in our brain. Strokes, or other injuries to the brain can do the same.
Treatments can be varied – different strokes for different folks, if I can use that pun. Sometimes just emotional support is needed, sometimes biochemical. Something relatively new in psychotherapy – Acceptance and Committment Therapy (ACT) is promising. So are monitored and controlled psychedelics. Severe depression can be successfully treated with electroconvulsive therapy (ECT), which causes changes in brain chemistry that can quickly reverse symptoms.
I have gone through two severe depressions in my life. One requiring a trial of antidepressents, and a lot of “talk therapy,” and emotional support, taking over a year. One, after a very sudden onset of severe depression caused by having to take tamoxifen after breast cancer. After taking two doses of anti-depressant medication, I could, literally, see and feel the black clouds lifting away.
I am glad for Sen. Fetterman’s success. I’m sure it will take time for him to recover from his stroke, and the stress of D.C. will not make it easy. But he has incredible resources (particularly Giselle and family), both medically and personally, that many people with mental illnesses cannot access. And mental health is every bit as important as good medical treatment. We need to offer it freely, as a society, and as humans, in our hearts and in our minds. We are all here to help walk each other home, as Ram Dass said.
