CAMBRIDGE, Mass. (AP) — An experimental vaccine against the coronavirus showed encouraging results in very early testing, triggering hoped-for immune responses in eight healthy, middle-aged volunteers, its maker announced Monday.
Funny how vaccines are being developed by the scientists Fat Nixon is now blaming for the Trump Pandemic death toll. Guess they must be feeling really guilty…
Without absolutely independent confirmation that this is an effective vaccine, and zero evidence they’re cooking the books on safety testing, I’m sorry to say I’m treating anything our own government is involved with as total snake oil.
Not sure how much a vaccine-- right now, today-- would be of help…
Excerpt:
Cellphone location data suggests that demonstrators at anti-lockdown protests – some of which have been connected with Covid-19 cases – are often traveling hundreds of miles to events, returning to all parts of their states, and even crossing into neighboring ones.
The data, provided to the Guardian by the progressive campaign group the Committee to Protect Medicare, raises the prospect that the protests will play a role in spreading the coronavirus epidemic to areas which have, so far, experienced relatively few infections.
The good news here is this is additional evidence that a vaccine is feasible. There has been considerable discussion centered around a proposition that coronavirus affects the immune system and represses a normal immune response.
These are still early days, early days. This is not a vaccine yet.
The race is on. Several vaccines have shown promise. None of them will be out before early next year. The early winter wave could be a disaster.
I heard somewhere there are no approved vaccines yet for any of the coronaviruses, which demonstrates that it’s a tricky business, but when I tried to google I got only stuff about the current one.
The vaccine by Cambridge, Massachusetts-based Moderna Inc
Moderna is the firm that used to have Moncef Slaoui on its board.
As noted yesterday:
As things stand, I expect that’s correct.
Google stopped being a good search engine a while ago. It is mostly a little better version of the Yahoo search engine. Totally tied to selling shit and giving surface answers.
Finally good news
Harsh but fair.
So, I hate to be Eeyore peeing on this good news, but there is still conflicting information on whether people who’ve had it and recovered are immune. If not, well, we need to hope that it at least lessens severity and long-term damage.
AAbsolutely. This write up is woefully lacking in details. Touting antibody response in humans without making public Phase I results.
Phase I was in mice. What they did was jump to Phase II in humans PRIOR to results in mice who were injected with CoV. Ordinarily, the mice receives dose of vaccine to determine dosing range. Once they have range then mice are injected with virus and monitored for immunegeneicity response & IG titer levels & length of response based on various doses.
Instead, “fast track” means they are simultaneously monitoring results in mice & humans post injection of virus. IOWs they are flying blindly.
There is no data from Phase I results to watch for deleterious effects onset nor transient efficacy
We are just gonna wait & see.
Fauci is not releasing Phase I results until data “makes sense”. Which is code for there are not enough data points to determine trend nor be predictive of response in terms of safety nor efficacy.
Two humans having antibody response is woefully inadequate & anything can happen. Media pumping hope & Moderna stock rising.
Now what could possibly go wrong as we continue to monitor the data in the Phase I mice, post injection of virus?
From the article:
Which stands a fair chance of the lower-dose versions still causing whatever damage is being found with the high-dose version, just more slowly.
This is correct. Try Medscape & Military.com
The only coronavirus vaccine out there is for chickens. Which farmers use and is effective with known risk of fatality in chickens. IOWs several will die. Not an acceptable risk in humans.
SARS nor MERS have vaccine, neither does HIV.
SARS and MERS pretty much disappeared. Other human corona viruses are mild. There’s simply no money to be made generating vaccines.
“shows promise” is mandatory language if you want to keep your funding. It means nothing in the bio-med world. COVID19 doesn’t play by the rules. No one is comfortable saying the presence of antibodies is protective and many are outright saying it is not. Most vaccines go through trial and error but they all produce antibodies. Just not serum neutralizing ones for the target organism. Hope this pans out but won’t be surprised if it does not.
Dow up over 820 pts as I type.
Wow. But that’s AP, they’re just chronically superficial and inaccurate. And they’ve been that way for as long as I can remember, since the Eighties anyway. As far as what we’re seeing here, I’m guessing it’s fundamentally a discordant mix of decent professionals trying to do their jobs and out-of-control political appointees doing a perverted dance of venality over top of them. I’m just glad at the obvious depth of knowledge in biology we have thanks to you and others in the group. We’ll be glad for your help as time goes on.