A Real Vaccine Before the Election? It’d Take a Miracle. | Talking Points Memo

They have already gone into production on a couple of the drugs - betting that they will work. If they don’t then all those vaccines get tossed. I believe it’s the US govt that’s bank rolling the early production - though the Gates Foundation may be in on it too.

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Johnson & Johnson might be the dark horse in the vaccine game even though they got a later start. Their vaccine has a 98% efficacy.

Researchers said 98 per cent of participants in the study whose data was available had neutralising antibodies, which help the body fight off pathogens, a month after they received the vaccine.

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We are still waiting on the “BETTER and LOWER COST” health care insurance trump promised 3.5 years ago. The latest promised date for release of the plan was “by the end of August” which was a month ago. It’s much like the way trump pays his bills. He doesn’t. He expected folks to forget. If they don’t he threatens to sue them and throws more money at lawyers than his original bill was worth thus driving himself further into debt. But he’s “the king of debt” he has loudly proclaimed. This is the behavior we have seen repeated tine and again. This is the world’s worst businessman. A moving Ponzi scheme.

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Induction of antibodies that neutralize virus in tissue culture does not always correlate with protection, so the 98% reported by J&J may not mean much. Besides, J&J uses a variant of the technology used by Astra Zenaca/Oxford - an attenuated Adenovirus carrier of COVID virus dna. The safety issues with that vaccine have not been resolved.

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It’s interesting that an administration that has spent four years claiming that “experts” don’t know as much as people with “common sense” did not anticipate that common sense might convince people that a rushed vaccine might not be a good idea.

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Wasn’t a tissue culture experiment. It was a phase ll trial with 1,000 participants
They are starting a phase lll trial with 60,000 people now. The only drawback is that it MAY not be as effective in people over 65. They need more older people in the phase lll trial.

Nearly 1,000 healthy adults participated in the clinical trial, which began after Johnson & Johnson saw that the vaccine provided strong immune protection when tested on monkeys.

The company began the latest phase of the trials on Wednesday when it began a 60,000-person trial. If results are successful, the trial would be another step on the path to a viable coronavirus vaccine.

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His Rose Garden Covid testing plan was a bit of a laugher.

The White House has a Rose Garden event today celebrating a covid testing contract they already announced in August. pic.twitter.com/3Ztsj88Aqw

— Kelly O'Donnell (@KellyO) September 28, 2020
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I hope that works, because I have a couple of ounces of that.

Joe’s going to ask him about it tomorrow night. And then Joe’s going to confirm Trump, Ivanka, Melania, the two boys and Rudy will be taking the first injections, on television for all to see. Yeah.

Wear a mask, use leeches and read tea leaves…

My Son in Law will get the Moderna phase 3 vacine next week.

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Curses. Nature wins again!

1 shot too, I think.

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Like the FDA will even review it. There will be a rubber stamp to get it out on 11/1

One thing that bothers me (in addition to the incredibly low bar for efficacy) is that no one has discussed longevity of protection? In natural infections antibodies last just 3-4 months IF a person developed them, and IF antibodies are sufficient to protect a person from infection. I certainly hope that they are also tracking longevity of protection, because a vaccine that lasts a month or two before needing to be readministered will not provide much protection in communities where people can’t get another injection easily.

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And the thing the Trumpies don’t seem to understand … you rush a miracle man, you get rotten miracles.

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Nope. Efficacy and “produces detectable antibodies” aren’t the same thing.

It’s like the difference between “actually puts the fire out” and “well, we see water coming out of the nozzle” when evaluating a (type A) fire extinguisher.

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So much is getting overlooked -
What if the virus comes in at 70%, but most people who do get sick are black? Or mostly women? Or over the age of 65? Or black women over 65?
How do you know what group can or can’t take it?

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Interesting. The faster they get results, the more likely the vaccine is ineffective. Doesn’t do much for Trump’s chances at winning re-election. A really good vaccine won’t be proven until New Year’s Day, but a really bad one can be shit-canned by Halloween.

It must really suck to be Trump right now. All that money from Fred, but no soul and no fucking brains to do anything constructive with it. I guess you can’t have everything.

I don’t think it works that way. You get “results” by having people show infection in the control group. If a smaller number (or none) of the vaccined group show infection in that time, then you likely have an effective vaccine. The “faster” they get “results” is a function of how much covid-19 is running around to infect people, not of the effectiveness of the vaccine.

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